Overview:
Exagen is a patient-focused and discovery-driven life sciences company dedicated to transforming the care continuum for patients suffering from debilitating and chronic autoimmune diseases. Our goal is to enable rheumatologists to improve care for patients through the differential diagnosis, prognosis, and monitoring of complex autoimmune and autoimmune-related diseases, including lupus and rheumatoid arthritis. By leveraging our proprietary Cell-Bound Complement Activation Products, or CB-CAPs, technology, we help get to the real cause of a patient’s symptoms and guide their journey to improved health.
The Assay Development Team at Exagen, Inc., extensively spans across the organization, engaging in projects that involve collaboration and work with members of diverse project teams. The successful candidate will work in a fast-paced environment and will work closely with the Bioinformatics, Laboratory, and Quality Teams. As Senior Scientist, you will be responsible for developing new assays, designing experiments for validation to meet current regulatory requirements and coordinating specimen testing with the new assay in CLIA lab. In addition, the Senior Scientist is responsible for reviewing data, troubleshooting, reporting results, documentation, and providing direction to other scientists. You will utilize your knowledge of immunology and flow-cytometry to help the team launch innovative and high-quality assays, from inception through planning and transfer to the clinical lab.
Responsibilities:
Note: Other duties may be assigned.
- Responsible for developing multi-parameter flow cytometry assays for use in autoimmune disease characterization, in the field of immunology.
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Designs strategies and experiments to develop assays based on experience as well as knowledge of immune system and immune mediated diseases.
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Performs experiments to validate flow reagents, assays and analyzes and compiles data in a report.
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Communicates results to functional teams
- Responsible for appropriate documentation meeting applicable regulatory and quality standards for novel flow assay launch.
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Troubleshoots own projects and also provides help to other scientists with their projects.
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May oversee day-to-day activities of other associates and train/mentor junior scientists.
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Searches, Investigates, and supports development of new assays.
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Write and review standard operating procedures, validation protocols and reports for the department.
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Knowledge of state-of-the-art techniques, principles and developments in the field of clinical flow cytometry.
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Works under minimal supervision.
Qualifications:
Knowledge and Skills:
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Strong knowledge of flow cytometry and immunology.
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2+ years’ experience designing, performing, and analyzing flow cytometry experiments,
- 2+ years’ experience developing assays on FACR Lyric, FACS Canto or another flow cytometer.
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Good understanding of data analysis using FlowJo, FCS Express, or equivalent software package.
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Demonstrated ability to interpret and present data of moderate to high complexity.
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Assay development experience in CLIA, CAP or NY-state regulated environment preferred
- Excellent analytical and problem-solving skills.
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Effective written and oral communication skills.
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Ability to keep accurate, and complete records.
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Ability to follow established policies and procedures.
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Strong team player who has a proven track record of collaborating on teams.
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Effectively works in a matrixed environment.
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Self-motivated with a strong work ethic.
Education and Experience:
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PhD in Immunology or a related life science discipline with 2+ years of relevant laboratory experience; or MS degree with 6+ years industry or relevant experience.
- Minimum of 6 years of experience in flow cytometry.
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Prior experience developing and validating multi-color flow cytometry assays, preferably in a clinical laboratory setting
Salary range: $120,000 - $170,000