20 Best Senior Scientist jobs (Hiring Now!)

Senior Scientist - Gene-to-Structure
Helix BioStructures LLC. —Indianapolis, IN
Experience with protein engineering and/or design approaches. The scientist will be expected to improve upon current state-of-the-art methods to accelerate…
Estimated: $92.1K - $117K a year
Quick Apply
Senior Research Scientist (Dark Web Monitoring)
Pindrop —Remote
Master and/or PhDs in a quantitative field (Computer Science, Mathematics, Engineering, Artificial Intelligence, etc.) required. Unlimited Paid Time Off (PTO).
Estimated: $149K - $189K a year
Quick Apply
2h
Senior Scientist – Analytical Development (AD) Synthetic Molecules – Early Development
Takeda Pharmaceutical —Boston, MA
Influences and supports initiatives related to driving scientific and technical improvement within function and potentially cross-functionally.
$133,000 - $209,000 a year
19h
Senior Scientist, Process Analytics
Takeda Pharmaceutical —Boston, MA
Your work also involves developing significant technical strategies and serving as a technical resource within the department for analytical challenges.
$133,000 - $209,000 a year
19h
Senior Associate Scientist, Molecular Discovery
Pfizer —La Jolla, CA
Understand principles and have experience with some modern molecular biology techniques (primer design, vector design, PCR, gel extraction, restriction cloning,…
$64,600 - $107,600 a year
2d
Senior Scientist Manufacturing - Cell Culture
Andelyn Biosciences —Columbus, OH
Experience in highly regulated field preferred. The Senior Scientist will aid in production efforts to deliver all products in a timely, compliant, and fiscally…
$83,267 - $88,910 a year
Quick Apply
5d
Senior Research Administrator
Dana-Farber Cancer Institute —Boston, MA
Extensive experience analyzing grant data through research, comprehension and application of regulations, policies, and procedures including NIH and other…
Estimated: $73.9K - $93.6K a year
8d
Senior Scientist AI/LLM
SimonMed Imaging MSO, LLC —Scottsdale, AZ
Lead others in translating algorithms into commercially viable products and services, develop, deploy and apply analytics, and research and deploy emerging…
Estimated: $108K - $137K a year
Quick Apply
3d
Associate/ Senior Associate Scientist in Protein Engineering (Contract to Hire)
BioMap Inc. —Palo Alto, CA
Help develop the high-throughput flow cytometry and plate-reader analysis platform. Help design the DNA constructs, and generate the synthetic DNA library by…
Estimated: $83.2K - $105K a year
Quick Apply
1d
Principal Investigator/Senior Scientist
Alturas Analytics, Inc. —Moscow, ID
Graduate degree (M.S. or Ph.D.) in chemistry, or related field, plus 2 years work experience in a bioanalytical CRO *or* a Bachelor’s degree in chemistry, or…
Estimated: $81.4K - $103K a year
Senior Scientist II, Biology
Brightseed —South San Francisco, CA
Normally requires a PhD in cell biology, molecular biology, biochemistry, or related biological field; may include post-doctoral experience.
$160,000 - $185,000 a year
1h
Senior Scientist - Product Development
Premier Research Labs —Austin, TX
Bachelor’s Degree in a science field, with 10 + years work experience. Evaluate new and existing ingredients, recommend and provide technical support to…
$82,500 - $87,600 a year
Senior Scientist- Environmental Health
JVM Solutions —Baton Rouge, LA
Understanding of air monitoring strategies, selecting action levels, interpreting air monitoring results and understanding any needed actions to take in the…
Estimated: $68.9K - $87.3K a year
Quick Apply
7d
Senior Staff Research Scientist
Vanderbilt University —Tennessee
Please note, all candidates selected for an offer of employment are subject to pre-employment background checks, which may include but are not limited to, based…
Estimated: $66K - $83.6K a year
Senior Clinical Research Coordinator
Evolution Research Group —Staten Island, NY
Manage studies with Principal Investigator, Site Director, and Recruitment Manager to develop effective programs for study enrollment.
$30 - $38 an hour
Quick Apply
13d
Senior Proteomics Scientist
Sapient —San Diego, CA
Must have a PhD in Chemistry, chemical engineering, bioengineering, biochemistry, biology, or related scientific field.
$170,000 - $190,000 a year
Quick Apply
14d
Senior Scientist I - Solid Dosage Forms
AbbVie —North Chicago, IL
Maintain a high level of productivity in the lab and/or pilot plant and cGMP manufacturing facilities. Provide technical expertise for marketed products and…
Estimated: $76.6K - $97K a year
Senior Scientist, Toxicology
AbbVie —North Chicago, IL
PhD in Molecular toxicology, Immunology, Pharmacology, Cell/Molecular Biology or related field with typically 0 to 5 years of academic or industry experience in…
Estimated: $103K - $130K a year
Quick Apply
8d
Senior Scientist
Merck Sharp & Dohme —Boston, MA
This individual will be expected to design and execute multiple cell based assays with deep comprehension of cell signaling to implement assay automation, new…
Estimated: $117K - $148K a year
4d
Senior Scientist
Pfizer —Cambridge, MA
The ideal candidate will have expertise in culturing CNS cell types, performing functional genomics in CNS relevant cell systems, and in leveraging high…
$88,300 - $147,100 a year
11d

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Senior Scientist - Gene-to-Structure

Helix BioStructures LLC. Indianapolis, IN

Quick Apply

Job Details

Full-time Estimated: $92.1K - $117K a year

Benefits

Relocation assistance
Health insurance
Dental insurance
Paid time off
Vision insurance
401(k) matching
Flexible schedule

Qualifications

Protein purification
Biochemistry
Management
Doctoral degree
Data structures
3 years
Project management
Doctor of Philosophy
Biophysics
Data collection
Leadership
Communication skills

Full Job Description

Senior Scientist - Gene-to-Structure

Helix BioStructures, LLC (HBS) is a contract research organization based in Indianapolis, Indiana, providing early drug discovery services to the biopharmaceutical industry. HBS maintains a full suite of services that encompass chemical & structural analysis, protein production, computational modeling, and design. HBS’s core and most popular services are structural biology imaging techniques: X-ray Crystallography and Cryo-EM. HBS was founded in 2018 and has grown considerably. We are looking to add an experienced senior scientist to join our Indianapolis-based team.

Main Responsibilities

This senior-level scientist will support our protein production and structural biology pipelines by producing proteins and setting up crystallization and/or cryo-EM experiments, interfacing with our clients, and writing technical project reports. The scientist will be expected to improve upon current state-of-the-art methods to accelerate research processes. This scientist will also be responsible for managing and supporting the team, planning & tracking all projects to produce and deliver high-quality work to our clients. A proven track record in managing people and projects with a deep understanding of protein construct design, expression, and purification of challenging proteins, biophysical characterization, and structural biology techniques is essential.

Highly desirable hands-on experiences include:

(a) Broad experience in protein production, both expression and purification (mammalian and prokaryotic)

(b) Biochemical, biophysical, and structural characterization of over-expressed and purified proteins.

(d) Cryo-EM grid preparation, data collection, and processing.

(e) Structure building and refinement program usage to phase difficult data sets.

In addition to expertise in crystallography and/or cryo-EM, this scientist will employ a range of experimental strategies (biochemical, biophysical, and/or computational) to support our client’s structure-based drug discovery, antibody discovery, and/or protein engineering. Accordingly, proficiency and a passion for exploring the structural basis of protein-protein and protein-ligand interactions are essential. The successful candidate will be a technical expert who can lead from the bench and collaborate with colleagues on multiple projects in parallel. Overall, you will be an outstanding protein scientist and structural biologist, collaborator, project and people leader who will significantly impact our portfolio with the unique opportunity to help drive discovery projects from inception to early development.

Additional Responsibilities

- Document experimental data and communicate research priorities, progress, and results with clients/project teams.

- Provide the team with project details, priorities, technical and scientific guidance, deliverables, and timelines.

- The candidate will be responsible for managing the team and all projects and providing support for project success.

- This candidate will manage his/her direct reports and provide all the support they need.

- The candidate will be responsible for timely updates on project statuses, reporting to their supervisor informally and to Helix’s customers by formal report writing and oral presentations.

Required Qualifications

- Ph.D. in biochemistry, biophysics, protein engineering, and/or structural biology with experience on multiple challenging protein targets. Productive postdoctoral training and/or industry experience is expected.

- Industry experience: 3-7 years post-Ph.D. (not including time as an academic postdoc).

- Demonstrated competency in protein expression and purification strategies using bacterial, insect, and/or mammalian cell lines.

- Demonstrated knowledge of construct design for structural/biophysical studies and biophysical characterization of proteins.

- Extensive experience in protein X-ray crystallography from protein sample assessment, crystallization, optimization, and data collection to structure determination and refinement.

- Experience with model building and refinement software, such as Phenix, Autoproc, CCP4, Chimera, Rosetta, ShelX, Coot, and Pymol.

- Experience with crystallization robots and standard analytical techniques associated with assessing protein quality during purification.

- Extensive experience reproducing and advanced optimization of crystal hits to produce diffraction-quality crystals.

- Extensive experience with co-crystallization and soaking techniques to help produce ligand-bound protein structures.

- Demonstrated experience and knowledge in people and project management.

- Strong leadership, written and oral communication skills, and attention to detail.

Additional qualifications

- Hands-on experience engineering protein constructs and optimizing the production of protein targets for structural and functional studies.

- Experience in biophysical characterization tools and strategies.

- Ability to generate and characterize milligram quantities of high-quality protein reagents

- Experience with protein engineering and/or design approaches.

- Analysis, design, and/or computational approaches to investigate ligand-protein complexes.

- Experience with Cryo-EM is a plus, especially grid vitrification, screening, and data processing using RELION.

- Lead and provide technical and scientific guidance to the team and manage all projects to produce high-quality results and meet the timeline.

- Excellent communication, interpersonal, organizational, and management skills.

- Fearless attitude to tackle longstanding complex problems.

Location

This position is based in Indianapolis, Indiana, and does offer a hybrid option. Interaction with external service vendors is also expected.

Physical Requirements

Able to lift 30 lb objects.

Able to visualize microscopic objects under microscopes.

Non-standard work schedule, travel, and lab safety

Able to adhere to safe work practices and perform lab work with appropriate personal protective equipment such as but not limited to safety goggles, facial mask, gloves, lab coat/ protective gowning, and closed-toe shoes. Able to work at flexible hours occasionally when performing time-sensitive experiments.

Other job details

- Eligible for Relocation Package

- Competitive Salary + Bonus

- Retirement (matching 401K)

- Health/Dental/Vision Insurance

- Company Apple computer

Helix BioStructures, LLC is an equal opportunity employer, and we embrace the increasingly diverse world around us. Helix BioStructures, LLC prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status.

Job Type: Full-time

Benefits:

401(k) matching
Dental insurance
Health insurance
Paid time off
Relocation assistance
Vision insurance

Experience level:

3 years

Schedule:

8 hour shift

Education:

Doctorate (Preferred)

Experience:

Industry: 3 years (Required)

Ability to Relocate:

Indianapolis, IN 46241: Relocate with an employer provided relocation package (Required)

Work Location: In person

Quick Apply

Senior Scientist jobs

Senior Scientist - Gene-to-Structure

Senior Research Scientist (Dark Web Monitoring)

Senior Scientist – Analytical Development (AD) Synthetic Molecules – Early Development

Senior Scientist, Process Analytics

Senior Associate Scientist, Molecular Discovery

Senior Scientist Manufacturing - Cell Culture

Senior Research Administrator

Senior Scientist AI/LLM

Associate/ Senior Associate Scientist in Protein Engineering (Contract to Hire)

Principal Investigator/Senior Scientist

Senior Scientist II, Biology

Senior Scientist - Product Development

Senior Scientist- Environmental Health

Senior Staff Research Scientist

Senior Clinical Research Coordinator

Senior Proteomics Scientist

Senior Scientist I - Solid Dosage Forms

Senior Scientist, Toxicology

Senior Scientist

Senior Scientist

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